What should someone expect with side effects?

Like many medications that impact metabolism and digestion, Mounjaro® (tirzepatide) may cause some side effects as the body adjusts. The most commonly reported symptoms include mild nausea, constipation, diarrhea, or general digestive discomfort. For most people, these effects are temporary and tend to improve over time, particularly when the medication dosage is increased gradually under the guidance of a healthcare provider. Clinical teams typically monitor progress closely and may recommend small adjustments—such as dietary changes, hydration strategies, or pacing dose escalations—to help minimize discomfort. It is uncommon for patients to discontinue treatment due to side effects, and with proper medical oversight, most individuals find these issues manageable as they work toward their health goals.