The medications Calibrate doctors prescribe in our Metabolic Reset are called GLP-1s (glucagon-like peptide-1s). Calibrate doctors prescribe a variety of GLP-1s, including semaglutide, liraglutide, tirzepatide, and dulaglutide. These GLP-1s are often referred to by their brand name, so you may have heard of these medications as Wegovy®, Ozempic®, Mounjaro™, or Saxenda®, to name a few.

All GLP-1s are clinically-tested, stimulant-free, and non-habit forming. GLP-1s address the underlying biology that is most important for weight loss, and help lower your set point, or the weight your body fights to stay at. GLP-1s are powerful, naturally-occurring hormones made by your gut that send signals to your brain to decrease your appetite, improve your metabolic system, and regulate your digestion so you can feel full longer and maximize nutrient absorption.

Regardless of which medication you’re prescribed, our commitment to all of our members remains the same—10% weight loss or your money back (see terms). Plus, if we can’t help you get access to a GLP-1 at $25/month or less you’re eligible for a refund (see details).

You can read more about GLP-1s here.

At Calibrate we have a team of insurance navigation experts to help you access an initial GLP-1 medication prescription for $25/month or less (after any deductible is met). We’ve helped tens of thousands of members access affordable GLP-1s. However, in the unlikely scenario that there is no path to a low-cost GLP-1 for you, you will be eligible for a refund (less a $250 fee for the initial doctor’s appointment). You will be eligible for this refund after 90 days from your doctor’s appointment – the full period of time it may take our team to explore all GLP-1 options for you (though the vast majority of members will get access sooner). See more details in our Refund Policy here. 

Unlike other weight loss medications, GLP-1s address the underlying biology that is most important for weight loss.

Phentermine, for example, is a stimulant (an amphetamine-like analogue) that reduces hunger so that you can more easily deprive yourself of calories—but again, eating less is not a sustainable solution for weight loss. Phentermine can also cause serious side effects including headaches, increased thirst, and significant elevation in blood pressure—which can force your heart to work harder and exacerbate any existing heart conditions. 

Contrave, another popular weight loss medication, is a combination of Wellbutrin (a medicine primarily used in the treatment of depression), and naltrexone (a drug used primarily in the prevention of alcohol or opioid abuse). Like phentermine, Contrave helps to reduce appetite, but does not address the most important underlying biology of weight gain.

GLP-1s are FDA-approved, clinically-tested, stimulant-free, and non-habit forming. Not only are they safe, but research shows that they are the most effective medications for sustainable weight loss, especially when combined with lifestyle changes like on Calibrate. GLP-1s are generally very well tolerated, with limited side effects. Many individuals don’t have any side effects at all. However, for those who do, nausea is the most common, and this typically resolves over the first few weeks. In the most recent clinical trials, at the highest dose, less than 5% of people discontinued GLP-1 medications because of side effects. With direct access to your Medical Team for help with titrating and managing side effects through secure messaging, we expect even less difficulty with side effects. Your Medical Team is available throughout the program for any questions about medication side effects or other medical concerns.

Your Calibrate doctor will review your required lab work and entire health history and can answer any questions you might have about medication interactions during your initial video doctor visit. GLP-1s (the medications that Calibrate doctors prescribe) can be safely taken with other common prescription medications—including those for blood pressure, thyroid, and diabetes—and have no contraindications with other prescription or over-the-counter medications. 

See if you're eligible for Calibrate at joinnow.joincalibrate.com

Calibrate members lose on average 15% of their body weight, per our clinically-reviewed Results Report. You can download the Calibrate Results Report here.

We're so confident that you'll succeed with Calibrate that we back it up with a money back promise. If you don’t lose at least of 10% your body weight within one year on our Metabolic Reset, you’re eligible for a refund (less the non-refundable $250 cost of the first doctor visit).  See terms here.

Calibrate is committed to helping members receive medication as quickly as possible, whether it’s their initial prescription or subsequent refills. Our team’s expertise spans data, pharmacy operations, medication coverage, patient access programs, insurance forms, and communicating directly with pharmacies. We have helped tens of thousands of members secure access to GLP-1s, and even amid inventory issues, we can provide members the best possible chance at getting GLP-1 access today.    

Our team monitors nationwide inventory for all FDA-approved GLP-1 medications.  Given the demand for GLP-1s and the time it takes to secure access, the sooner you join Calibrate, the sooner our team can start helping you obtain your doctor-prescribed GLP-1 medication.  

Once you sign up for Calibrate, you complete our Orientation phase, which includes getting lab work done ahead of your doctor visit, where you will be prescribed a GLP-1 as clinically appropriate. Since this process can take a few weeks, by signing up now, you are putting yourself in the best position to get GLP-1 access as soon as possible. 

Regardless of GLP-1 access, with Calibrate’s holistic program we’re confident you will achieve real results, and our promise is the same regardless of medication access: 10% weight loss or your money back.