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Trulicity® is a safe, FDA-approved medication for weight loss. Calibrate’s One Year Metabolic Reset has produced 2-3X better weight loss outcomes than using GLP-1 medication, like Trulicity®, alone.

All Calibrate members will be considered, as clinically appropriate and insurance eligible, for Trulicity®.

15% Average
Weight Loss

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Designed for your biology
not willpower

Through our purpose-built Metabolic Reset, Calibrate members achieve 15% weight loss on average—that's 2X the results achieved by most GLP-1s when used alone.

Doctor-prescribed GLP-1 medication

Your Calibrate doctor will explore a variety of GLP-1 options to find one that’s clinically appropriate for you and covered by your insurance.

1:1 bi-weekly video coaching

Together, with your dedicated Calibrate Coach, you’ll learn to make gradual lifestyle changes that ladder up to big wins.

Holistic Curriculum

Our evidence-based curriculum is designed to help you improve the Four Pillars of Metabolic Health: food, sleep, exercise, and emotional health.

Results Guaranteed

We’re so confident you’ll succeed with Calibrate that if you participate in our Metabolic Reset and don’t lose at least 10% of your body weight you’ll be eligible for a refund (see terms).

Backed by science   •   Backed by science   •   


Calibrate doctors prescribe medications called GLP-1s (glucagon-like peptide-1s) because research shows that, in combination with coaching and lifestyle change, GLP-1s are the most effective and safe long-term option for weight loss.

GLP-1s are powerful, naturally occurring hormones in your body that send signals to your brain to improve your metabolic function and regulate your digestion so that you feel fuller longer. The GLP-1 medications that Calibrate doctors prescribe work on the same receptors as the natural GLP-1 hormones.

Your Calibrate doctor will prescribe you the most effective and clinically appropriate GLP-1 medication that’s covered by your commercial insurance. We guarantee your monthly GLP-1 medication cost will be $25/month or less with insurance (after any deductible is met), or you’re eligible for a refund (see details).

Dulaglutide (Trulicity®)

Semaglutide (Wegovy™, Ozempic®, Rybelsus®)

Liraglutide (Saxenda®, Victoza®)



Our science-backed program combines prescription medication with virtual doctor visits, 1:1 accountability coaching, and a comprehensive curriculum to change the way you eat, sleep, exercise, and feel–for a metabolic reset that lasts.

Our Medical Leadership Team

Calibrate’s clinical advisors and medical team are some of the top weight and metabolic health experts and scientific researchers in the country.

Frequently Asked Questions