GLP-1s are FDA-approved and safe. They have been widely used since 2005 and are generally very well tolerated, with minimal side effects. For anyone with a personal or family history that might put them at a slightly higher risk for extremely rare side effects, we always err on the side of caution.
GLP-1s are FDA-approved, clinically-tested, stimulant-free, and non-habit forming. Not only are they safe, but research shows that they are the most effective medications for sustainable weight loss, especially when combined with lifestyle changes like on Calibrate. GLP-1s are generally very well tolerated, with limited side effects. Many individuals don’t have any side effects at all. However, for those who do, nausea is the most common, and this typically resolves over the first few weeks. In the most recent clinical trials, at the highest dose, less than 5% of people discontinued GLP-1 medications because of side effects. With direct access to your Medical Team for help with titrating and managing side effects through secure messaging, we expect even less difficulty with side effects. Your Medical Team is available throughout the program for any questions about medication side effects or other medical concerns.
The FDA-approved medications that are a part of the Metabolic Reset are called GLP-1s, and are clinically-tested, stimulant-free, and non-habit forming. Side effects are extremely rare, and most individuals who take a GLP-1 do not experience any. For those who do, nausea is the most common, and this typically resolves over the first few weeks of being on the medication. If you do experience any side effects, you’ll be able to reach out to your Clinical Team directly for support.
In the most recent clinical trials, less than 5% of people discontinued GLP-1 medications because of side effects.
Calibrate clinicians prescribe GLP-1s because research shows that they are the safest and most effective medication for sustainable weight loss, especially when combined with lifestyle changes like Calibrate supports. Many GLP-1s are taken via an injection. While an injection may sound scary, most members actually report injections being painless, quick, and easy. (It’s just under the skin—going into your fat instead of your muscle. The needle is ultra-fine, so it isn’t like a typical shot.) GLP-1s are self-administered either daily or weekly depending on the medication. Your Calibrate clinician can walk you through how this works and can also send you a short video to help. In addition, not only are injectables the medications we prescribe more effective, but they also have fewer and safer side effects than other weight loss medications.
Your Calibrate clinician will use your medical history and insurance coverage to prescribe the best GLP-1 for you and may prescribe you an oral GLP-1 option if injections are not a good fit. The Calibrate Medical Team is available to answer your questions about GLP-1s and to address other medical concerns you might have throughout your Calibrate year.