Designed in partnership with leading minds in obesity treatment and metabolic health, Calibrate is a holistic approach to weight loss that combines doctor-prescribed GLP-1 medication and 1:1 video coaching with lifestyle changes. The goal is to make gradual, science-backed changes to your food, sleep, exercise, and emotional health habits that ladder up to real results you can maintain—even after medication. And our members lose 18% weight loss, on average sustained over two years.
See our Pricing page for more details.
GLP-1s are FDA-approved and safe. They have been widely used since 2005 and are generally very well tolerated, with minimal side effects. For anyone with a personal or family history that might put them at a slightly higher risk for extremely rare side effects, we always err on the side of caution.
GLP-1s are FDA-approved, clinically-tested, stimulant-free, and non-habit forming. Not only are they safe, but research shows that they are the most effective medications for sustainable weight loss, especially when combined with lifestyle changes like on Calibrate. GLP-1s are generally very well tolerated, with limited side effects. Many individuals don’t have any side effects at all. However, for those who do, nausea is the most common, and this typically resolves over the first few weeks. In the most recent clinical trials, at the highest dose, less than 5% of people discontinued GLP-1 medications because of side effects. With direct access to your Medical Team for help with titrating and managing side effects through secure messaging, we expect even less difficulty with side effects. Your Medical Team is available throughout the program for any questions about medication side effects or other medical concerns.
The medications Calibrate doctors prescribe in our Metabolic Reset are called GLP-1s (glucagon-like peptide-1s). Calibrate doctors prescribe a variety of GLP-1s, including semaglutide, liraglutide, tirzepatide, and dulaglutide. These GLP-1s are often referred to by their brand name, so you may have heard of these medications as Wegovy®, Ozempic®, Mounjaro®, or Zepbound®, to name a few.
All GLP-1s are clinically-tested, stimulant-free, and non-habit forming. GLP-1s address the underlying biology that is most important for weight loss, and help lower your set point, or the weight your body fights to stay at. GLP-1s are powerful, naturally-occurring hormones made by your gut that send signals to your brain to decrease your appetite, improve your metabolic system, and regulate your digestion so you can feel full longer and maximize nutrient absorption.
Regardless of which medication you’re prescribed, our commitment to all of our members remains the same—10% weight loss or you're eligible for money back (see terms).
You can read more about GLP-1s here.
The FDA-approved medications that are a part of the One-Year Metabolic Reset are called GLP-1s, and are clinically-tested, stimulant-free, and non-habit forming. Side effects are extremely rare, and most individuals who take a GLP-1 do not experience any. For those who do, nausea is the most common, and this typically resolves over the first few weeks of being on the medication. If you do experience any side effects, you’ll be able to reach out to your Medical Team directly for support.
In the most recent clinical trials, less than 5% of people discontinued GLP-1 medications because of side effects. However, in the incredibly rare case that you have side effects that make you ineligible to participate in the program, you’d be offered the choice to stay in the program with a non-GLP-1 medication called metformin (if clinically appropriate) or to partially refund your program based on the amount of time you were able to participate.