Your Calibrate doctor will review your required lab work and entire health history and can answer any questions you might have about medication interactions during your initial video doctor visit. GLP-1s (the medications that Calibrate doctors prescribe) can be safely taken with other common prescription medications—including those for blood pressure, thyroid, and diabetes—and have no contraindications with other prescription or over-the-counter medications. 

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Calibrate doctors prescribe GLP-1s (glucagon-like peptide-1s) because research shows that, in combination with accountability coaching, they are the most effective and safe long-term medication for weight loss. GLP-1s prescribed through the Calibrate program include semaglutide (including under the brand name Wegovy®) liraglutide, and dulaglutide. 

All Calibrate members will be considered for Wegovy® as clinically appropriate and insurance eligible. We will work with your commercial/employer insurance to help get it covered for $25/month or less.

GLP-1s are FDA-approved, clinically-tested, stimulant-free, and non-habit forming. Not only are they safe, but research shows that they are the most effective medications for sustainable weight loss, especially when combined with lifestyle changes like on Calibrate. GLP-1s are generally very well tolerated, with limited side effects. Many individuals don’t have any side effects at all. However, for those who do, nausea is the most common, and this typically resolves over the first few weeks. In the most recent clinical trials, at the highest dose, less than 5% of people discontinued GLP-1 medications because of side effects. With direct access to your Medical Team for help with titrating and managing side effects through secure messaging, we expect even less difficulty with side effects. Your Medical Team is available throughout the program for any questions about medication side effects or other medical concerns.

Calibrate doctors prescribe GLP-1s because research shows that they are the safest and most effective medication for sustainable weight loss, especially when combined with lifestyle changes like Calibrate supports. Many GLP-1s are taken via an injection. While an injection may sound scary, most members actually report injections being painless, quick, and easy. (It’s just under the skin—going into your fat instead of your muscle. The needle is ultra-fine, so it isn’t like a typical shot.) GLP-1s are self-administered either daily or weekly depending on the medication. Your Calibrate doctor can walk you through how this works and can also send you a short video to help. In addition, not only are injectables the medications we prescribe more effective, but they also have fewer and safer side effects than other weight loss medications. 

Your Calibrate doctor will use your medical history and insurance coverage to prescribe the best GLP-1 for you and may prescribe you an oral GLP-1 option if injections are not a good fit. The Calibrate Medical Team is available to answer your questions about GLP-1s and to address other medical concerns you might have throughout your Calibrate year.

The FDA-approved medications that are a part of the One-Year Metabolic Reset are called GLP-1s, and are clinically-tested, stimulant-free, and non-habit forming. Side effects are extremely rare, and most individuals who take a GLP-1 do not experience any. For those who do, nausea is the most common, and this typically resolves over the first few weeks of being on the medication. If you do experience any side effects, you’ll be able to reach out to your Medical Team directly for support.

In the most recent clinical trials, less than 5% of people discontinued GLP-1 medications because of side effects. However, in the incredibly rare case that you have side effects that make you ineligible to participate in the program, you’d be offered the choice to stay in the program with a non-GLP-1 medication called metformin (if clinically appropriate) or to partially refund your program based on the amount of time you were able to participate.