Recapping the 2024 Calibrate Member Results Report

Medically reviewed by: Kristin Baier, MD, VP of Clinical Development

Since our launch in June 2020, Calibrate has been committed to member outcomes as our north star. 

We are the only program regularly publishing results for our entire member population who have completed at least one year of our program. We have changed the way weight loss results are reported and measured, setting the new standard of scientific rigor and transparency in a category that has historically lacked both.

In February 2024, we unveiled our latest Member Results Report, showcasing unprecedented success in our members’ weight loss and metabolic health outcomes. We’re recapping some of the key findings from the 2024 report here. 

Find out if you’re eligible: Get started. 

Calibrate weight loss results: Members lost 18% on average over 24 months

The 2024 Member Results Report highlights the remarkable achievements of a real-world cohort of 16,098 members—the largest to-date in the industry. 

Key findings include:

• An average weight loss of over 16% for 12 months
• An average weight loss of 18% for 24 months across the cohort
• An average 6.1 inch decrease in waist circumference from baseline to 12 months

These outcomes surpass those seen in clinical trials of leading GLP-1 medications such as  Wegovy®, Saxenda®, Ozempic®, Rybelsus®, and Trulicity®. Calibrate members also see better long-term, sustained results versus other weight loss programs.

Whereas participants of GLP-1 clinical trials rely on medication alone, Calibrate’s program utilizes GLP-1 medication in combination with 1:1 coaching, a dedicated medical team, and a physician-designed curriculum to help members stay accountable. With Calibrate, medication is one piece of a larger puzzle that leads to metabolic health improvements. Regardless of which medication they were prescribed, Calibrate members demonstrated significant and sustained results.

Members report higher satisfaction with their results after Calibrate, too: Of the cohort studied, nine out of ten stated that Calibrate is the most effective program they have ever tried. 

Improvements in key metabolic health markers like A1C

Calibrate’s comprehensive approach extends beyond weight loss, helping members make lifestyle changes to improve overall metabolic health. 

The 2024 report reiterates this emphasis: Study participants experienced significant improvements across various markers, including hemoglobin A1c, insulin, cholesterol, triglycerides, liver enzymes, waist circumference, and inflammation levels.

Here’s a closer look at those improvements: 

• For members who completed lab work at the end of their Calibrate Year, 98% demonstrated an improvement in at least one metabolic marker
• 78% of members who started the program with prediabetes or diabetes were able to achieve normal hemoglobin A1c levels at 12 months
• Improved HbA1c was observed in 81% of all members and healthy changes were seen for all other metabolic lab values (HDL, LDL, triglycerides, AST/ALT, hs-CRP and insulin) in 55% to >80%

Sustained behavioral change with Calibrate

The 2024 Member Results Report found that the impact of the Calibrate program extends to health behaviors, as well, with positive changes observed in food habits, exercise frequency, sleep quality, and emotional health. 

Here’s a little more detail on patient-reported habit changes:

• Calibrate members reported a 58% improvement in food habits, a 28% improvement in emotional health, a 50% improvement in energy levels, and a 27% improvement in overall health 
• Additional questions gathered more information for sleep and exercise habit changes, with 38% of members improving sleep and 49% improving exercise frequency

Notably, higher BMI categories saw more significant improvements, with members starting with a BMI over 40 experiencing a 69% improvement in food habits.

The 2024 Member Results Report shows that Calibrate works—and that’s a guarantee

Despite challenges such as medication supply disruptions and insurance coverage limitations, members achieved significant and sustained weight loss, showcasing the program's resilience and efficacy.

Over half, or 53.5% (n = 6,136 of 11,472), of members experienced at least one disruption (as defined by the last script not being sent to a local pharmacy and at least 13 weeks without a fill). Additionally, 8% (n = 923) of members experienced multiple disruptions.

Importantly, member satisfaction remains high, with the majority acknowledging Calibrate as the most effective program they've tried. The gradual and easy-to-integrate lifestyle changes, coupled with non-restrictive approaches, contribute to the program’s success and sustainability.

At Calibrate, we stand behind our results—so much so that our Results Money-Back Promise commits to achieving at least 10% weight loss for members at one year, or their money back. We guarantee at least 10% because research shows that 10% body weight loss meaningfully improves health outcomes and is sustainable. 

We’re proud to be the only program to make this commitment based on our track record of success. With each member we serve, Calibrate is truly changing the way the world treats weight.

Find out if you’re eligible: Get started. 

Your company may cover Calibrate as part of its benefits package. Learn more about Calibrate for employees. 

Appendix: Study methodology

Weight loss data represents all individuals who had reached at least 12 months in the Calibrate program by October 2023 and had verified access to GLP-1 medication for at least one month of the program (n=14,255), as well as smaller subsets of all members meeting same criteria who had continued to 18 and 24 months (n=4,845 and n=1,169, respectively). 

Waist circumference data represents all individuals in above cohorts who reported waist circumference at intake and one-year check-in (n=7,3737). Lab data represents all members in the above cohorts who had at least one lab measured at intake and one-year check-in (n=3,422); not all individuals in cohort successfully completed all labs, so individual lab result Ns vary as noted above.